Microscopy Primer
Light and Color
Microscope Basics
Special Techniques
Digital Imaging
Confocal Microscopy
Live-Cell Imaging
Microscopy Museum
Virtual Microscopy
Web Resources
License Info
Image Use
Custom Photos
Site Info
Contact Us

The Galleries:

Photo Gallery
Silicon Zoo
Chip Shots
DNA Gallery
Amino Acids
Religion Collection
Cocktail Collection
Screen Savers
Win Wallpaper
Mac Wallpaper
Movie Gallery

Phase Contrast Image Gallery

Squamous Cell Papilloma

A stained thin section of human elpithelial tissue exhibiting damage from squamous cell papilloma virus is illustrated below. As evidenced by the micrograph, combining phase contrast microscopy with classical histological staining techniques in pathological research often yields enhancement of cellular features.

Papillomas, also known as warts or corns, are benign (noncancerous) growths of the skin or mucous membranes and are caused by the Human Papilloma Virus (HPV). HPVs are very common and are only able to infect the epithelium of the skin.

While innocuous for the most part, some strains of this virus are associated with cellular changes that can eventually lead to cancer. There are two kinds of abnormal tissues caused by HPV that physicians can identify: condyloma (warts) and dysplasia (pre-cancer). While there is no cure for the virus at present, it generally does not require treatment. Most papillomas will go away on their own or can be tolerated if they are not in a pre-cancerous state. Surgical removal is the only treatment for disfiguring or potentially cancerous papillomas.

Over 65 virus types have been identified so far, based on DNA analysis. The genome of the virus is contained entirely on a double-stranded circular DNA molecule, which replicates entirely in the nucleus of the host cell. Usually, it replicates independently of the host genome, but will integrate into the DNA of the host cell on occasion, which could eventually make it a candidate as a vehicle for gene therapies.


Questions or comments? Send us an email.
© 1998-2022 by Michael W. Davidson and The Florida State University. All Rights Reserved. No images, graphics, scripts, or applets may be reproduced or used in any manner without permission from the copyright holders. Use of this website means you agree to all of the Legal Terms and Conditions set forth by the owners.
This website is maintained by our
Graphics & Web Programming Team
in collaboration with Optical Microscopy at the
National High Magnetic Field Laboratory.
Last modification: Friday, Nov 13, 2015 at 02:19 PM
Access Count Since April 12, 2000: 28416
For more information on microscope manufacturers,
use the buttons below to navigate to their websites: