Visit the
Molecular Expressions Website

Galleria
Photo Gallery
Silicon Zoo
Chip Shots
Screen Savers
Museum
Web Resources
Primer
Java Microscopy
Win Wallpaper
Mac Wallpaper
Publications
Custom Photos
Image Use
Contact Us
Search
Home

Chemical Crystal Movie Gallery

Niacinamide Movie #5

Niacinamide, a more water-soluble form of vitamin B-3, may play a key role in fighting aging and repairing damaged joint cartilage, which is typical in arthritis. As the amide form of niacin, niacinamide may prevent, and in some cases even reverse, Type 1 (insulin-dependent) diabetes.

Known also as nicotinamide, niacinamide does not produce flushing of the skin, as does niacin when doses exceed 50 milligrams. Natural sources of niacinamide include beef liver, brewer's yeast, halibut, chicken, sunflower seeds, and peanuts. Synthesized niacinamide is marketed in the form of tablets, capsules, oral solutions, and as injectable formulations, and reportedly aids the release of energy from consumed foods and promotes DNA biosynthesis. In the digestion of fats, production of sugars, and in tissue respiration, the coenzymes NAD and NADP incorporate available niacinamide into their structures. However, while niacin also helps regulate cholesterol, niacinamide does not.

At higher concentrations than the 25 milligrams per 2 pounds of body weight prescribed for diabetes, niacinamide acts as a natural tranquilizer and binds onto the same brain receptor sites as synthesized pharmaceuticals such as Valium. Certain research suggests that niacinamide protects the liver against cirrhosis and other alcohol-abuse induced damage, and some trials of the chemical indicate that when it is ingested four times a day at 500-milligram doses, canker sores are inhibited and healed. Deficiencies in vitamin B-3 result in pellagra, headaches, depression, and other symptoms, and because cigarette smoking decreases vitamin B-3 absorption, smokers may require supplemental niacin. Overdoses of niacinamide cause vomiting and diarrhea and can result in high blood sugar, high uric acid, liver damage, and heart arrhythmia.

Contributing Authors

Omar Alvarado, Thomas J. Fellers and Michael W. Davidson - National High Magnetic Field Laboratory, 1800 East Paul Dirac Dr., The Florida State University, Tallahassee, Florida, 32310.


BACK TO NIACINAMIDE INDEX

BACK TO THE BRIGHTFIELD IMAGE GALLERY

Questions or comments? Send us an email.
© 1995-2013 by Michael W. Davidson and The Florida State University. All Rights Reserved. No images, graphics, software, scripts, or applets may be reproduced or used in any manner without permission from the copyright holders. Use of this website means you agree to all of the Legal Terms and Conditions set forth by the owners.
This website is maintained by our
Graphics & Web Programming Team
in collaboration with Optical Microscopy at the
National High Magnetic Field Laboratory.
Last Modification Thursday, Jun 15, 2006 at 02:39 PM
Access Count Since September 17, 2002: 5844
Visit the website of our partner in introductory microscopy education: