Tacrolimus is an immunosuppressant that prolongs the survival of host and transplanted tissue in clinical trials of animal models of liver, kidney, heart, bone marrow, small bowel, pancreas, lung, skin, and cornea. The drug is very promising and has been demonstrated to suppress both humoral and cell-mediated immunity. Although the exact mechanism is unknown, tacrolimus appears to inhibit T-lymphocyte activation. Side effects include tremor, headache, diarrhea, hypertension, nausea, and renal dysfunction.
© 1995-2022 by Michael W. Davidson and The Florida State University. All Rights Reserved. No images, graphics, software, scripts, or applets may be reproduced or used in any manner without permission from the copyright holders. Use of this website means you agree to all of the Legal Terms and Conditions set forth by the owners.
This website is maintained by our