Mevinolin and it's relatives fluvastatin, pravastatin, and simvastatin are useful in helping to reduce cholesterol and other fat levels in the blood. They are also showing promise in helping to slow the progression of coronary atherosclerosis. These drugs work by blocking enzymes that synthesize cholesterol, while simultaneously increasing the level of high-density lipoproteins. Side effects include itching, skin rash, headache, dizziness, and blurred vision.