Often referred to as vitamin H, biotin is a water-soluble constituent of the B-complex group of vitamins. The biochemical is essential to the human body for proper growth and metabolism, and is believed to play a central role in DNA replication and transcription. Good dietary sources of biotin include liver, kidney, soy flour, egg yolk, cereal grains, and yeast. Biotin deficiencies are relatively rare, occurring most often in those fed intravenously without proper supplements and those who consume large amounts of raw egg whites on a regular basis. Fatigue, depression, rash, nausea, muscle pain, hair loss, and anemia are among the most common symptoms of biotin deficiency. Consequently, some have suggested that vitamin E is capable of curing baldness and dermatitis as well as alleviating muscle pain and depression, but there is no substantial evidence supporting these claims.