Didanosine (DDI or 2',3'-dideoxyinosine)

Photograph of Didanocine (DDI or 2',3'-dideoxyinosine) under the microscope.

Didanosine is marketed in the United States and Canada under the trade name Videx. This nucleotide antagonist appears to help prevent the reproduction of the AIDS virus in infected patients whose health has deteriorated during treatment with AZT. Didanosine has been demonstrated to increase the number of CD4 helper white blood cells that are usually depressed in advanced stages of AIDS. Unfortunately, didanosine is known to produce some serious side effects including inflammation of the pancreas and painful nerve damage.

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