Metoclopramide is a gastrointestinal drug that is often used to combat the nausea that occurs in patients who are undergoing cancer treatment with anticancer agents. The drug is also useful to treat the symptoms of diabetic gastroparesis, and it relieves symptoms such as nausea, vomiting, the feeling of fullness after meals and loss of appetite. In some instances, metoclopramide is used to treat heartburn in patients who suffer from esophageal injury. Side effects include chills, difficulty in swallowing, dizziness, irregular heartbeat, fever, and increase in blood pressure.