Candesartan Cilexetil (Atacand)

Photograph of Candesartan Cilexetil (Atacand) under the microscope.

Candesartan cilexetil is a prodrug that is hydrolyzed to candesartan during adsorption from the gastrointestinal tract. The agent is a selective AT(1) subtype angiotensin II receptor antagonist that serves to lower elevated blood pressure levels. Candesartan works by preventing the binding of angiotensin II to the AT(1) receptor, resulting in blockage of the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Side effects include dizziness, lightheadedness, headache, sore throat, nasal congestion, runny nose, and back pain.

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