As the oldest artificial sweetener, saccharin is currently making a comeback after medical research pegged it as a demon rather than a savior for weight-conscious individuals and diabetics that cannot tolerate natural sugars without a severe glucose reaction because of insulin problems.

Sugar rationing during the two World Wars made saccharin a product in high demand in Europe and the United States as a sugar substitute. By the 1960s, diet fads and concerns with an ever-burgeoning American populace pushed the growth of saccharin as a low-calorie sugar substitute into orbit in the familiar pink package of Sweet 'N Low.